Distorted vision and vision loss usually become noticeable in a persons sixties or seventies and tend to worsen over time. Longevinex lrv is a low dose hormetic overthecounter otc oral resveratrol rv based matrix of red wine solids, vitamin d 3 and inositol hexaphosphate ip6 with established bioavailability, safety, and shortterm efficacy against the earliest signs of human atherosclerosis, murine cardiac reperfusion injury, clinical retinal neovascularization, and stem cell survival. Rare spontaneous remissions from agerelated macular degeneration amd suggest the human retina has large regenerative capacity, even in advanced age. Longevinex has been awarded a us patent which describes a nutraceutical matrix designed to enhance the absorption, bioavailability, and molecular stability of resveratrol in a manner similar to a proprietary resveratrol drug now undergoing human clinical investigation. Moreover, the investigators found a reduction in macular pathophysiology during spectraldomain optical coherence tomography in 3 of 7 patients and profound multiline improvements in visual acuity in 4 of 7. The resveratrol pill that our subject chose had been previously reported by our clinical team to produce measurable improvements in vision among 16 of 17 otherwise helpless macular degeneration. Oct 11, 2018 unfortunately, even after treatment, wet macular degeneration can recur, and you may need more treatments. But your peripheral side vision will still be normal. Indicates that the study sponsor or investigator has submitted summary results information for a clinical study to clinicaltrials.
Longevinex dilates widens arteries and improves blood flow upon physical exertion twice that of plain resveratrol. Nov 11, 2019 agerelated macular degeneration amd is a common, polygenic disease in which multiple genetic variants, as well as environmental and lifestyle factors, contribute to disease risk, each adding a small to moderate amount of increased risk. Please be aware that longevinex has no control over delivery of the product once it leaves our shipping department. New research shows a way to preserve your precious eyesight.
Seven evidences longevinex works to promote longevity in. Stuart richer od phd faao has been studying the molecular effects of this drug on the aging eye specifically eyes with agerelated macular degeneration. Longevinex improves human atrophic aged related macular. Jun 22, 2018 a choice was presented to the eyecare community with the publication of mortality data concerning combined strokeagerelated macular degeneration amd patients. Jun 15, 2012 a nonprescription nutraceutical agent might help restore lost vision in patients with neovascular agerelated macular degeneration amd who are otherwise unresponsive to antivegf therapy, according to a series of case studies presented at this years annual arvo meeting in ft. Now with added nucleotides to support dna repair us patent no. Longevinex improves human atrophic agedrelated macular degeneration amd photoreceptor retinal pigment epithelium mediated dark adaptation stuart richer 1,2,3, lawrence ulanski ii 1,3, anish bhandari 4,5 and natalia popenko 4,5. Sardi, resveratrol partners lcc las vegas, nv makers of longevinex capsules provided clinical research laboratory development funding to s. The mechanism of chloroquine and hydroxychloroquine toxicity is not well understood.
Any of three fdaapproved drugs, avastin, lucentis and eylea, are needleinjected into the white of the eye to diminish the formation of these abnormal blood vessels. Can supplement containing resveratrol help wet macular. Family members of patients with macular degeneration urged to undergo dark adaptation test could detecthalt vision loss up to 4 years before it occurs. Agerelated macular degeneration, nutrition, epigenetics, hormesis, copper, iron, calcium, environmental stress disclosure. Dry macular degeneration may first develop in one eye and then affect both. Longevinex improves human atrophic agedrelated macular. Stuart richer od, phd, in a small study of elderly subjects with dry macular degeneration, discovered that roughly 86% of subjects significantly reduced the time it took for their eyes to adapt to the dark when taking longevinex. Regulatory bodies and customs agents in countries outside the u.
Unfortunately, even after treatment, wet macular degeneration can recur, and you may need more treatments. What used to be health secrets arent so secretive any more. Resveratrol can help prevent age related macular degeneration amd eye conditions resveratol may help prevent damage caused by age related macular degeneration. Agerelated macular degeneration amd is the most common cause of impaired vision and. The macula is the part of the retina responsible for clear vision in your direct line of sight. The best preliminary evidence suggests that resveratrol supplements may be helpful for agerelated macular degeneration amd, an incurable eye condition that affects up to 11 million americans. Over time, however, some people experience a gradual worsening of vision that may affect one or both eyes. May 07, 2012 can supplement containing resveratrol help wet macular degeneration. Longevinex improves human atrophic agedrelated macular degeneration amd photoreceptor retinal pigment epithelium mediated dark adaptation.
First oral agent to quell invasive macular degeneration. So far, the optimal dose of resveratrol has not been established. Longevinex is an over the counter nutritional supplement containing resveratrol, vitamin d, rice bran ip6, and quercetin. Feb 28, 2020 agerelated macular degeneration amd is a problem with your retina. Resveratrol can help prevent age related macular degeneration. October 2019 more than a decade after the groundbreaking launch of antivegf drugs for the treatment of wet agerelated macular degeneration amd, gene therapy is being tested and touted as a potential oneanddone solution antivegf drugs arent perfect. If youre in the early stages of agerelated macular degeneration you may not have symptoms. We suggest you recommend the shipping agency united parcel ups, dhl, fedex that serves you the best when you place your order. Because of this, people with the condition must test their own vision regularly and.
Nutraceutical longevinex reduces time it takes older. Family members of patients with macular degeneration urged to. We previously reported our shortterm findings for dry and wet agerelated macular degeneration amd patients. Resveratrol for exudative agerelated macular degeneration full. A characteristic of agerelated macular degeneration amd is the. Some anti aging products that do work it is well known in the medical and scientific world that there are some products that will. Agerelated macular degeneration also called macular degeneration, amd or armd is deterioration of the macula, which is the small central area of the retina of the eye that controls visual acuity the health of the macula determines our ability to read, recognize faces, drive, watch television, use a computer, and perform any other visual task that requires us to see fine. Agerelated macular degeneration is an eye disease that is a leading cause of vision loss in older people in developed countries. Agerelated macular degeneration amd is the most common cause of impaired vision and blindness in the elderly. There is no proven remedy for this insidious sightrobbing disease. Nutraceutical longevinex reduces time it takes older eyes.
Resveratrol restores vision in macular degeneration patients. Longevinex is a unique matrix of specially stabilized molecules shown to activate longevity genes. In a small study, daily supplementation with the nutraceutical product longevinex, resveratrol partners, las vegas, nv was shown to improve and even stabilize dark adaptation dathe earliest functional sign of dry agerelated macular degeneration amd. Currently there is no effective treatment for the dry form of this disease. Age related macular degeneration amd is the leading cause of vision loss in. In one previous study this supplement seemed to reduce the amount of a waste product in the retina called lipofuscin, which is linked to the development of macular degeneration. Dry macular degeneration symptoms and causes mayo clinic. Regeneration of hyaluronan gel to thicken hair, produce smooth skin and lubricate joints and cushion nerves.
Jun 28, 2019 dry macular degeneration is a common eye disorder among people over 50. Dark adaptation time is an eye test that can predict the onset of macular degeneration. Agerelated macular degeneration amd is the leading cause of agerelated blindness. Richer has also published images showing regeneration of damaged tissues at the back of the eye that are not normally. First oral agent to quell invasive macular degeneration, restore lost. The hope is one day macular degeneration will be detected at a predisease stage and completely prevented. The response to longevinex was bilateral in 5 of 7 patients and, in one patient, was noted after 1 month of longevinex therapy. Macular degeneration, also known as agerelated macular degeneration amd or armd, is a medical condition which may result in blurred or no vision in the center of the visual field. Jun 10, 20 let me clarify, because its a little confusing.
Mar 23, 2020 the mechanism of chloroquine and hydroxychloroquine toxicity is not well understood. Resveratrolbased nutraceutical improves symptoms of age. Dry macular degeneration is a common eye disorder among people over 50. Agerelated macular degeneration amd is a problem with your retina. October 2019 more than a decade after the groundbreaking launch of antivegf drugs for the treatment of wet agerelated macular degeneration amd, gene therapy is being tested and touted as a potential oneanddone solution. Chloroquine has an affinity for pigmented melanincontaining structures, which may explain its toxic properties in the eye. Resveratrol in longevinex is microencapsulated enfolded in plant dextrins and starches to protect from degradation by light, heat, oxygen. Resveratrol and fraud, the bigger issue as far as we now know, this case of scientific misconduct occurred in the lab of one researcher with, at. The fact a nutraceutical has been demonstrated for the first time to reverse a predictive measure for macular degeneration is a monumental development in preventive medicine says dr.
Dry macular degeneration is diagnosed when yellowish spots known as drusen begin to accumulate in and around the macula. Observation of human retinal remodeling in octogenarians. It happens when a part of the retina called the macula is damaged. Now, for the time ever, researchers report that an oral nutraceutical may rapidly restore vision to otherwise hopeless patients who face permanent loss. Nutraceutical longevinex reduces time it takes older eyes to adapt to the dark dark adaptation test predicts future onset of macular degeneration. May 19, 2017 longevinex, formulated by bill sardi, is not new. Dry amd is an early stage of the disease and may result from the aging and thinning of macular tissues, depositing of pigment in the macula or a combination of the two processes. Macular degeneration affects millions of senior adults.
Jan 16, 2012 resveratrol and fraud, the bigger issue as far as we now know, this case of scientific misconduct occurred in the lab of one researcher with, at best, a modest reputation in his field. Surprisingly, many consumers reported that they also experienced a major improvement in their eyesighteven the reversing macular degeneration. Longevinex is an rv matrix of small molecular weight. It affects about 10% of people between ages 66 and 74 and as many as 30% of those. The first sign you may notice is a gradual or sudden change in the quality of your vision or that. Dec 31, 2012 dry macular degeneration is a leading cause of blindness among senior americans and is called dry because there is no swelling due to accumulation of blood serum at the back of the eyes as there is in wet macular degeneration. Resveratrol is a molecule extracted from the skin of grapes in red wine. Only in recent years has there been a reliable way to treat wet macular degeneration, a disorder where abnormal blood vessels invade the visual center macula of the eyes. Agerelated macular degeneration beyond the agerelated. Melanin serves as a freeradical stabilizer and can bind toxins, including retinotoxic drugs. The research focuses on an oral nutraceutical, longevinex resveratrol partners, llc, which delivers high doses of vitamin d and resveratrolthe powerful antioxidant that is found predominantly in the skins of red grapes and other fruits. Amd is the leading cause of vision loss in people over age 60. Researchers discover a nutraceutical longevinex shortens the time it takes for eyes to adapt to the dark. Resveratrol may be key in amd stroke patient treatments.
First evidence that dark adaptation in amd patients may. A significant increase in the drusenfree macular area dfma of the patient occurred following 2. Provision of luteinzeaxanthin to protect the eyes and skin from solar radiation aging. The agerelated eye disease study areds the large, multicenter national collaborative study, directed at the wilmer institute by principal investigator, dr. Longevinex protects the rodent heart from experimentallyinduced heart attack better than plain resveratrol. It causes blurred or reduced central vision, due to thinning of the macula makuluh.
We present examples of robust improvement of retinal structure and function using an otc oral resveratrol rv based nutritional supplement called longevinex or lrv circa 2004, resveratrol partners, llc, las vegas, nv, usa. Observation of human retinal remodeling in octogenarians with. May 21, 2012 agerelated macular degeneration amd is the leading cause of agerelated blindness. Subtle abnormalities indicating changes in vision may occur in a persons forties or fifties. May 08, 2017 researchers discover a nutraceutical longevinex shortens the time it takes for eyes to adapt to the dark. Richer has reported the visual rescue of patients who failed drug therapy for wet macular degeneration with the experimental use of longevinex in humans. Longevinex improves human atrophic agedrelated macular degeneration amd photoreceptor retinal pigment epithelium mediated dark adaptation stuart richer 1,2,3, lawrence ulanski ii 1,3, anish bhandari 4,5 and natalia popenko 4,5 1departments of optometry and ophthalmology, preventative ocular medicine and residencies, usa. Today we report long term two to three year clinical. Resveratrol based oral nutritional supplement produces longterm beneficial effects on structure and visual function in human patients. Agerelated macular degeneration genetics home reference. With longevinexs proven long shelf life, buy quantity instead and save the multiple shipping costs. That means it had reversed the process that is predictive of macular degeneration. Provision of vitamin b1 thiamin as benfotiamine, a known antiaging nutrient.
You cannot see fine details, whether you are looking at something close or far. Improved visual acuity and retinal integrity with resveratrol based. Resveratrol based oral nutritional supplement produces long. Nutraceutical longevinex reduces time it takes older eyes to adapt to the dark. Statins, caloric restriction and longevinex in a oneeyed patient.
Longevinex 100mg formula healthy aging purity products. First oral agent to quell invasive macular degeneration, restore lost vision in otherwise hopeless cases. Dry macular degeneration is a leading cause of blindness among senior americans and is called dry because there is no swelling due to accumulation of blood serum at the back of the eyes as there is in wet macular degeneration. Agerelated macular degeneration news all about vision. I took longevinex for 3 montas because a radio program touted improved vision even for those who have macular degeneration. Does longevinex resveratrol really help for agerelated macular degeneration.